mPEG-PLLA Copolymer
●mPEG-PLLA Product Description
As a homopolymer of L-lactic acid, PLLA has relatively high crystallinity and glass transition temperature, providing good mechanical strength and thermal stability. Its degradation period is typically several months to approximately two years, and its degradation product is lactic acid, a naturally occurring metabolite in the human body.
By adjusting the block ratio and molecular weight of mPEG and PLLA, the hydrophilic/hydrophobic balance, self-assembly morphology, and degradation behavior of the copolymer can be precisely controlled.
mPEG-PLLA has good biocompatibility and excellent design flexibility, with broad applications in long-acting drug delivery microspheres, postoperative anti-adhesion membranes, high-strength tissue engineering scaffolds, and aesthetic medicine applications such as facial filling and contouring.
The molecular weight distribution of the product is ≤2.0. Customized molecular weights and viscosities are available according to customer requirements.
Product Index:
| Item | Unit | Standard | Reference Standard | Method | Result |
| Appearance | / | Pale Yellow to White powder | / | Visual inspection | Conforms |
| Intrinsic viscosity [η] | dL/g | / | YY/T 0661-2017 | 25℃ in Chloroform | 0.42 |
| Weight-average molecular weight | g/mol | / | / | GPC | 42163 |
| Dispersity (D) | / | ≤2.5 | / | GPC | 1.33 |
| Molecular weight of PEG | / | 800-1200 | / | GPC | 951 |
| Moisture | % | ≤0.5 | YY/T 0661-2017 | KFT | 0.23 |
| Monomer residue | % | ≤2 | YY/T 0661-2017 | GC | 0.42 |
| Solvent residue (Total) | ppm | ICH limit value | YY/T 0661-2017 | GC | Conforms |
| Single Solvent Residue | ppm | ICH Q3C | YY/T 0661-2017 | GC | Conforms |
| Heavy metal residue (Pb) | μg/g | ≤10 | YY/T 0661-2017 | 0841 Heavy metal detection method in Chinese Pharmacopoeia | Conforms |
Storage Conditions: Store in a low-temperature refrigerator at 2-8℃.
